Category: Cardiology and cardiovascular disease

Repurposing existing drugs for cardiovascular risk management: a focus on methotrexate

Arduino A Mangoni MD, PhD, FRCP, FRACP, Sara Tommasi PhD, Angelo Zinellu PhD, Salvatore Sotgia MSc, Ciriaco Carru PhD, Matteo Piga MD, Gian Luca Erre MD

Article Type

Review

Published

This review discusses the current challenges in the management of cardiovascular disease; the available evidence on the effects of methotrexate on inflammation, blood pressure, and surrogate markers of arterial function; suggestions for future research directions; and practical considerations with the use of methotrexate in this context.

Read more

Primary genetic disorders affecting high density lipoprotein (HDL)

Constantine E Kosmas MD, PhD, Delia Silverio MD, Andreas Sourlas, Frank Garcia MD, Peter D Montan MD, Eliscer Guzman MD

Article Type

Review

Published

This review aims to describe certain genetic disorders associated with either low or high plasma HDL-C and discuss their clinical features, associated risk for cardiovascular events, and treatment options.

Read more

Spectral Doppler and automated software-guided ultrasound assessment of bilateral common carotid intima-media thickness in spondyloarthritis: is there a correlation with clinical findings?

José Alexandre Mendonça PhD, Beatriz Bisetto de Andrade MD, José Luis Braga de Aquino PhD, Vania Aparecida Leandro-Merhi PhD, Guilherme B Damian MD

Article Type

Original Research

Published

This study evaluates the correlation between articular and carotid ultrasound data and laboratory and clinical variables in patients with spondyloarthritis.

Read more

Register for alerts

I would like to be contacted by Drugs in Context when new articles are posted.