Article Type
Review
Published
This review examines the therapeutic efficacy and safety of ezetimibe in combination therapy with statins and its potential side effects.
Articles
Article Type
Review
Published
Over the past ten years, sorafenib has been the only systemic agent approved for first-line treatment of patients with unresectable hepatocellular carcinoma (HCC) and in a second-line setting, most investigational drugs have failed to provide better survival outcomes than placebo. However, in 2016, data from the RESORCE trial, a phase 3 study evaluating regorafenib in HCC patients who experience disease progression after first-line treatment with sorafenib, have shown a 2.8-month median survival benefit over placebo (10.6 versus 7.8 months).
Article Type
Review
Published
This review explores the current place of metformin in the management of gestational diabetes and type 2 diabetes during pregnancy and lactation.
Article Type
Review
Published
This article reviews the latest information available regarding the treatment of hypertension with combination therapy.
Article Type
Editorial
Published
This editorial describes the results of the most recent clinical trials on the use of immunotherapies in renal cell carcinoma and research for reliable biomarkers of tumour response in this setting, as well as the role of the gut microbiome and tumour microenvironment in the development of future therapeutic strategies.