Review
This narrative review discusses the pathophysiological mechanisms that are currently believed to lead to diabetic peripheral neuropathy (DPN), DPN screening and diagnosis, methods of prevention, and treatment options to address DPN symptoms and complications.
Original Research
This article reviews the literature on the impact of antidepressants on depressive symptom severity, quality of life, morbidity, and mortality in patients with heart failure.
Review
This article serves to provide clinicians with updated information about novel antidepressant medications, augmentation strategies with atypical antipsychotics, over-the-counter medications, as well as nonpharmaceutical treatments that should be considered when treating each individual patient who remains symptomatic despite treatment efforts.
Review
Prescribing of antidepressant treatment (ADT) for major depressive disorder (MDD) has increased substantially over the last two decades. In this paper, the authors discuss the evidence that supports the use of ADT based on FDA approvals, data from randomized controlled trials or meta-analyses and where these are not available, the authors discuss and apply theoretical pharmacodynamic principles to help guide treatment choice in MDD.