monoclonal Archives - Drugs in Context

Guselkumab for the treatment of psoriasis – evidence to date

Miguel Nogueira MD, Tiago Torres MD, PhD

Article Type

Review

Published

09 Jul 2019

This review highlights the evidence available to date for the use of guselkumab for the treatment of psoriasis. The results of the recent ECLIPSE trial are addressed.

The role of anti-vascular endothelial growth factor (anti-VEGF) in the management of proliferative diabetic retinopathy

Yue Zhao MD, Rishi P Singh MD

Article Type

Review

Published

13 Aug 2018

This review discusses recent clinical trials and guidelines for anti-VEGF use in proliferative diabetic retinopathy.

Metastatic squamous cell non-small-cell lung cancer (NSCLC): disrupting the drug treatment paradigm with immunotherapies

Sarah L Scarpace

Article Type

Review

Published

14 Oct 2015

Lung cancer is the third most commonly diagnosed cancer and the leading cause of cancer-related death in the United States. This paper provides an overview of drug therapy options for squamous cell NSCLC with a focus on the evidence and clinical application of the anti-PD1 therapies. A comparison of the dosing, administration, indications, and differences in the measurement of PD-L1 expression in the clinical trials of nivolumab and pembrolizumab is also provided.