Rectal neuroendocrine carcinoma: case report of a rare entity and perspective review of promising agents

Gabriela Antelo MD, Cinta Hierro MD, MSc, Juan Pablo Fernández MD, Eduardo Baena MD, Cristina Bugés MD, Laura Layos MD, José Luis Manzano MD, Mónica Caro MD, Ricard Mesia MD, PhD

Article Type

Review

Published

This article discusses the current management of this rare entity and provide an overview of the most relevant molecular findings, whilst illustrating the potential value that prescreening panels can offer, searching for actionable targets (MSI/dMMR, PD-L1, BRAFv600E) to guide therapy with promising agents that could fill a void in this disease.

Read more

Facing the COVID-19 outbreak in children with cancer

Antonio Ruggiero MD, Alberto Romano MD, Giorgio Attinà MD

Article Type

Editorial

Published

This editorial discusses the current COVID-19 outbreak and underlines that hygienic educational programs are fundamental and must be continued and implemented especially for immunosuppressed children.

Read more

Tumor lysis syndrome in childhood malignancies

Wing Lum Cheung MBBS, MRCPCH, Kam Lun Hon MBBS, MD (CUHK), FAAP, FCCM, Cheuk Man Fung MBChB, MRCPCH, Alexander KC Leung MBBS, FRCPC, FRCP (UK & Irel), FRCPCH, FAAP

Article Type

Review

Published

This review provides an update on the current understanding, evaluation, and management of tumor lysis syndrome in childhood malignancies.

Read more

Register for alerts

I would like to be contacted by Drugs in Context when new articles are posted.