Review
With the prevalence of type 2 diabetes increasing, this article discusses how it is essential that healthcare professionals assess how their patients’ current diabetes treatment is being managed to avoid further weight gain in those who are already overweight or obese.
Review
This narrative review summarizes the current state of information available regarding the treatment of gestational diabetes mellitus.
Review
This narrative review explores the expanding indications, risks and opportunities associated with insulin infusions and potential options for improved safety.
Case Report
Type 2 diabetes mellitus (T2DM) management is complex, with few patients successfully achieving recommended glycemic targets with monotherapy, most progressing to combination therapy, and many eventually requiring insulin. Sodium glucose cotransporter 2 (SGLT2) inhibitors are an emerging class of antidiabetes agents with an insulin-independent mechanism of action, making them suitable for use in combination with any other class of antidiabetes agents, including insulin. In this review the evaluates a 78-week, randomized, double-blind, placebo controlled trial investigating the impact of empagliflozin, an SGLT2 inhibitor, as add-on to basal insulin in patients with inadequate glycemic control on basal insulin, with or without metformin and/or a sulfonylurea.
Review
Once changes in lifestyle have failed, treatment for gestational diabetes mellitus remains a matter of debate. In this article the authors review the evidence for glyburide and metformin, and discuss the role of insulin. Also, recommendations for postpartum screening and how to manage patients who are breastfeeding are described.